Development of MobileNetV2 for CT-Scan Lung Classification Using Transfer Learning

Authors

  • Daffa Fadhil Rajendra Universitas Amikom Yogyakarta
  • Ajie Kusuma Wardhana Universitas Amikom Yogyakarta

DOI:

https://doi.org/10.30871/jaic.v9i5.10282

Keywords:

Lung Cancer, CT Scan, MobileNetV2, Transfer Learning, Deep Learning

Abstract

Lung cancer is one of the leading causes of cancer-related deaths worldwide, making early detection crucial for improving patient survival rates. This study proposes an automated classification approach based on deep learning using the MobileNetV2 architecture to identify three categories of lung CT scan images: normal, benign, and malignant. The dataset used is the augmented IQ-OTH/NCCD Lung Cancer Dataset, consisting of 3,609 images with a resolution of 224×224 pixels. All images underwent preprocessing steps including RGB conversion, pixel rescaling, and normalization. The MobileNetV2 model was modified by adding a GlobalAveragePooling2D layer, a dense layer, and dropout to reduce overfitting risk. Training was conducted for 28 epochs using the optimizer Adam, followed by evaluation using accuracy, precision, recall, and F1-score metrics. The model was tested on unseen data and validated using Stratified 5-Fold Cross Validation. The testing results showed an overall accuracy of 97%, with a perfect recall score (1.00) for the malignant class. The cross-validation yielded an average accuracy of 97.26% with a standard deviation of ±0.66%, indicating consistent model performance. Given its lightweight architecture and high accuracy, MobileNetV2 has the potential to be implemented as a decision support system in medical image analysis.

Downloads

Download data is not yet available.

References

[1] H. Sung et al., “Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries,” CA Cancer J Clin, vol. 71, no. 3, pp. 209–249, May 2021, doi: 10.3322/caac.21660.

[2] J. Ferlay et al., “Cancer statistics for the year 2020: An overview,” Int J Cancer, vol. 149, no. 4, pp. 778–789, 2021, doi: 10.1002/ijc.33588.

[3] E. Edelman Saul et al., “The challenges of implementing low-dose computed tomography for lung cancer screening in low- and middle-income countries,” Nat Cancer, vol. 1, no. 12, pp. 1140–1152, Nov. 2020, doi: 10.1038/s43018-020-00142-z.

[4] M. A. Thanoon, M. A. Zulkifley, M. A. A. Mohd Zainuri, and S. R. Abdani, “A Review of Deep Learning Techniques for Lung Cancer Screening and Diagnosis Based on CT Images,” Diagnostics, vol. 13, no. 16, p. 2617, Aug. 2023, doi: 10.3390/diagnostics13162617.

[5] M. Q. Shatnawi, Q. Abuein, and R. Al-Quraan, “Deep learning-based approach to diagnose lung cancer using CT-scan images,” Intell Based Med, vol. 11, p. 100188, Dec. 2025, doi: 10.1016/j.ibmed.2024.100188.

[6] W. Wulaningsih, C. Villamaria, A. Akram, J. Benemile, F. Croce, and J. Watkins, “Deep Learning Models for Predicting Malignancy Risk in CT-Detected Pulmonary Nodules: A Systematic Review and Meta-analysis,” Lung, vol. 202, no. 5, pp. 625–636, 2024, doi: 10.1007/s00408-024-00706-1.

[7] H. Jiang, S. Tang, W. Liu, and Y. Zhang, “Deep learning for COVID-19 chest CT (computed tomography) image analysis: A lesson from lung cancer,” Comput Struct Biotechnol J, vol. 19, pp. 1391–1399, 2021, doi: 10.1016/j.csbj.2021.02.016.

[8] O. Ukwandu, H. Hindy, and E. Ukwandu, “An evaluation of lightweight deep learning techniques in medical imaging for high precision COVID-19 diagnostics,” Healthcare Analytics, vol. 2, p. 100096, Nov. 2022, doi: 10.1016/j.health.2022.100096.

[9] J. Zheng et al., “Pulmonary nodule risk classification in adenocarcinoma from CT images using deep CNN with scale transfer module,” IET Image Process, vol. 14, no. 8, pp. 1481–1489, Jun. 2020, doi: 10.1049/iet-ipr.2019.0248.

[10] R. Klangbunrueang, P. Pookduang, W. Chansanam, and T. Lunrasri, “AI-Powered Lung Cancer Detection: Assessing VGG16 and CNN Architectures for CT Scan Image Classification,” Informatics, vol. 12, no. 1, p. 18, Feb. 2025, doi: 10.3390/informatics12010018.

[11] M. Kalkan, M. S. Guzel, F. Ekinci, E. Akcapinar Sezer, and T. Asuroglu, “Comparative Analysis of Deep Learning Methods on CT Images for Lung Cancer Specification,” Cancers (Basel), vol. 16, no. 19, p. 3321, Sep. 2024, doi: 10.3390/cancers16193321.

[12] B. D. S. Isnayni Sugma Rachmatika, Lailil Muflikhah, “Deteksi Mutasi Pada Kanker Paru Melalui Citra CT-Scan Penerapan Model Algoritma Convolutional Neural Networks (CNN)dan Optimizer Adam,” Jurnal Pengembangan Teknologi Informasi Dan Ilmu Komputer, vol. Vol 8 No 9, 2024, [Online]. Available: https://j-ptiik.ub.ac.id/index.php/j-ptiik/article/view/14134/6317

[13] Z. Gao, Y. Tian, S.-C. Lin, and J. Lin, “A CT Image Classification Network Framework for Lung Tumors Based on Pre-trained MobileNetV2 Model and Transfer learning, And Its Application and Market Analysis in the Medical field,” Jan. 2025, [Online]. Available: http://arxiv.org/abs/2501.04996

[14] A. Saha, S. M. Ganie, P. K. D. Pramanik, R. K. Yadav, S. Mallik, and Z. Zhao, “VER-Net: a hybrid transfer learning model for lung cancer detection using CT scan images,” BMC Med Imaging, vol. 24, no. 1, p. 120, May 2024, doi: 10.1186/s12880-024-01238-z.

[15] S. Velu, “An efficient, lightweight MobileNetV2-based fine-tuned model for COVID-19 detection using chest X-ray images,” Mathematical Biosciences and Engineering, vol. 20, no. 5, pp. 8400–8427, 2023, doi: 10.3934/mbe.2023368.

[16] A. Gudur, H. Sivaraman, and V. Vimal, “International Journal of Intelligent Systems And Applications In Engineering Deep Learning-Based Detection of Lung Nodules in CT Scans for Cancer Screening,” Original Research Paper International Journal of Intelligent Systems and Applications in Engineering IJISAE, vol. 2023, no. 7s, pp. 20–28, 2023, [Online]. Available: www.ijisae.org

[17] M. Aftab et al., “AI in Oncology: Transforming Cancer Detection through Machine Learning and Deep Learning Applications,” Jan. 2025, [Online]. Available: http://arxiv.org/abs/2501.15489

[18] M. Aparna and B. S. Rao, “A novel automated deep learning approach for Alzheimer’s disease classification,” IAES International Journal of Artificial Intelligence (IJ-AI), vol. 12, no. 1, p. 451, Mar. 2023, doi: 10.11591/ijai.v12.i1.pp451-458.

Downloads

Published

2025-10-16

How to Cite

[1]
D. F. Rajendra and A. K. Wardhana, “Development of MobileNetV2 for CT-Scan Lung Classification Using Transfer Learning”, JAIC, vol. 9, no. 5, pp. 2703–2710, Oct. 2025.

Similar Articles

1 2 3 4 5 > >> 

You may also start an advanced similarity search for this article.